Research projects of current students
- Daniela Keilberg
- Start date: Oct 2009
- Nationality: German
- Diploma thesis:
“Cis - and trans-acting pole-targeting determinants of RomR in Myxococcus xanthus“ (2009) Martin-Luther-Universität Halle
- Research group:
AG Søgaard-Andersen, Department of Ecophysiology, MPI
- Research project description
The soil bacterium M. xanthus moves by gliding motility and possesses two gliding engines, the S-System for movement in groups of cells, and the A-System for single-cell movement. In my project I focus on the Response Regulator RomR, which is required for the A-System. RomR localizes asymmetrically to the cell poles with a large cluster at the lagging cell pole and a small cluster at the leading pole. The localization of the protein RomR is dynamic. When the cell changes direction of gliding by a cell reversal the large cluster switches from the old lagging cell pole to the new lagging cell pole. Using biochemical and molecular approaches I concentrate on finding interacting proteins of RomR and factors, which trigger RomR to the poles to find out more about how the A-System works.
